Audrey Tautou stars as the eponymous character in this French comedy drama directed by Jean-Pierre Jeunet. When she discovers a box of childhood memorabilia belonging to someone who lived in her Montmarte apartment years ago, Amélie Poulain decides to track down the now-elderly owner and return the box to him.

His response inspires her to continue to strive to bring happiness into the lives of others and so she sends her father's garden gnome off on a tour around the world, helps her colleague Georgette (Isabelle Nanty) to find a boyfriend and comes up with an imaginative way to stop a local grocer from being cruel to his employee.

However, even though Amélie brings happiness to her neighbours, her own happiness proves elusive until she meets the handsome Nino (Mathieu Kassovitz)...